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ginkgo-cloud-lab

ginkgo-cloud-lab

Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and ordering workflows.

Ginkgo Cloud Lab

Overview

Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.

The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.

The catalog is organized into Expression & Purification (in vitro / cell-free / E. coli / Pichia), Characterization & Assay, Method & Target Onboarding, and Specialty. Pick a protocol below, then read its reference file for inputs, outputs, the automated workflow, and ordering details.

Available Protocols

Expression & Purification - In vitro

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | IVT mRNA/circRNA Synthesis | qPCR (mRNA or circRNA, 384-well) | $99/sample | up to 12 business days | Certified |

Expression & Purification - Cell-free (E. coli CFPS)

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Validate sequence expression | Go/no-go titer + purity (up to 1800 bp) | $39/sample | up to 10 days | Certified | | Optimize expression conditions | DoE across 24 conditions | $199/sample | up to 11 days | Certified | | Express + quantify (HiBiT) | Luminescence, no purification | $39/sample | up to 11 days | Certified | | Express + purify (A280) | Strep-tag, A280 yield | $149/sample | up to 11 days | Certified | | Express + purify minibinder | Strep-tag, A280, LabChip | $149/sample | up to 11 days | Certified | | Express + purify (A280 + LabChip) | Strep-tag, A280 + purity/size | $159/sample | up to 12 days | Certified |

Expression & Purification - E. coli

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Express + quantify (HiBiT) | Luminescence (up to 384 constructs) | $79/sample | up to 3 weeks | Certified | | Express + purify (A280) | His-tag, A280 yield | $199/sample | up to 3 weeks | Certified | | Express + purify minibinder | His-tag, A280 yield | $199/sample | up to 3 weeks | Certified | | Express + purify (A280 + LabChip) | His-tag, A280 + purity/size | $209/sample | up to 3 weeks | Certified |

Expression & Purification - Pichia

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Express + quantify (LabChip) | Secreted protein, size/purity (up to 96) | $89/sample | up to 4 weeks | Certified (New) |

Characterization & Assay

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Express + thermal shift | SYPRO Orange Tm (Tonset, TM1-3) | $159/sample | up to 12 days | Certified | | Detect enzymatic products (Echo-MS) | Substrate/product by Echo-MS | $44/sample | up to 13 days | Beta |

Method & Target Onboarding

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Onboard Echo-MS method | Calibration curve, LOD/LOQ | $799/molecule | up to 3 weeks | Certified | | Onboard SPR target | Validated SPR capture method | $1,399/target | up to 4 weeks | Beta |

Specialty

| Protocol | Readout | Price | Turnaround | Status | |---|---|---|---|---| | Generate fluorescent pixel art | UV photo, 7-color E. coli palette | $25/plate | up to 7 days | Beta |

Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target).

Choosing a Protocol

  • Quick expressibility screen? Cell-free HiBiT ($39) or Validate sequence expression ($39).
  • Need purified protein + yield? A280 tiers (cell-free or E. coli); add LabChip for purity/size.
  • Difficult / membrane / disulfide / cofactor targets? Cell-free Optimize (24-condition DoE).
  • Secreted or eukaryotic targets? Pichia expression.
  • Screening de novo binders/minibinders? Cell-free or E. coli minibinder tiers, then SPR onboarding for kinetics.
  • Enzyme activity / biocatalysis? Echo-MS enzymatic detection (onboard the analyte method first).
  • Stability / developability ranking? Thermal shift assay.
  • RNA (mRNA/circRNA)? IVT synthesis + qPCR.

General Ordering Workflow

  1. Select a protocol at https://cloud.ginkgo.bio/protocols
  2. Configure parameters (number of proteins/samples/molecules/targets, replicates, plates)
  3. Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; vendor catalog numbers for onboarding)
  4. Add any special requirements in the Additional Details field
  5. Provide an email, agree to the protocol terms, and add to cart / submit to receive a feasibility report and price quote

For protocols not listed above, use the EstiMate chat (https://cloud.ginkgo.bio/estimate) to describe a custom protocol in plain language and receive a compatibility assessment and pricing.

Authentication

Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.

Key Infrastructure

  • RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
  • Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
  • 70+ integrated instruments: Agilent Bravo liquid handlers, Beckman/Labcyte Echo acoustic dispensers, BMG PHERAstar / Tecan Spark readers, Revvity LabChip, Bio-Rad CFX Opus, Nicoya Alto SPR, SciEx Echo-MS, Inheco/Cytomat incubators, and more
  • Nebula: Ginkgo's autonomous lab facility in Boston, MA

安装中心

可直接安装到 9 个框架（另有 Cursor / Windsurf 需转换为 rules 格式）。悬停可查看各框架的技能目录。

方式一 · 复制提示词（推荐）

粘贴给你的 Claude Code，它会自己完成下载和安装（安装文件直接取自原始仓库）

请帮我安装技能「ginkgo-cloud-lab」：
1. 从原始仓库下载技能文件：https://raw.githubusercontent.com/K-Dense-AI/scientific-agent-skills/main/skills/ginkgo-cloud-lab/SKILL.md（GitHub 上的 SKILL.md 原始文件）
2. 保存为 ~/.claude/skills/ginkgo-cloud-lab/SKILL.md（目录不存在则创建）
3. 确认文件存在后，告诉我安装结果

方式二 · 命令行安装

npx CLI 跨平台可用（自动检测本机 Agent）；PowerShell 方式无需安装任何东西

npx ailine-skills add ginkgo-cloud-lab
New-Item -ItemType Directory -Force "$HOME\.claude\skills\ginkgo-cloud-lab" | Out-Null; curl.exe -fsSL "https://raw.githubusercontent.com/K-Dense-AI/scientific-agent-skills/main/skills/ginkgo-cloud-lab/SKILL.md" -o "$HOME\.claude\skills\ginkgo-cloud-lab\SKILL.md"

方式三 · 前往原始仓库

第三方技能不由本站分发安装文件，请从原始仓库获取（上方命令/提示词已直连原始文件）

前往 GitHub 仓库 ↗查看 SKILL.md 原文件